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Picropodophyllotoxin

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产品名称: Picropodophyllotoxin
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简单介绍

CAS:477-47-4Formula:C22H22O8MW:414.408Appearance:Solid


Picropodophyllotoxin  的详细介绍
IGF1R inhibitor

Additional Information

Product #P-2721
CAS #477-47-4
FormulaC22 H22 O8
MW414.408
AppearanceSolid
SolubilitySoluble in DMSO (100 mM), and ethanol 
Storage Temp+4°C
Therapeutic AreaOncological Disorders
UsePPP is an insulin-like, cell-permeable cis-cyclolignan compound that acts as a non-competitive, potent, and specific inhibitor of growth factor-I receptor kinase

Additional Information

MDL NumberMFCD01742647
ChemACXX1599094-6
InChIInChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
SMILESCOc1cc(cc(c1OC)OC)[C@@H]2c3cc4c(cc3[C@@H]([C@@H]5[C@@H]2C(=O)OC5)O)OCO4
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