PI3-K gamma Inhibitor, AS-605240

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产品名称: PI3-K gamma Inhibitor, AS-605240

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简单介绍

CAS:648450-29-7Formula:C12H7N3O2SMW:257.27Appearance:PinktoreddishSolidPurity:98%byHPLC

PI3-K gamma Inhibitor, AS-605240 的详细介绍

Cell-permeable. A potent and selective inhibitor of PI 3-kinase (PI3K) (IC= 8 nM). Displays >33-fold selectivity over PI3K and PI3K and 7.5-fold selectivity over PI3K.

Additional Information

Synonyms	5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione
Product #	P-2395
CAS #	648450-29-7
Chemical Name	5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione
Formula	C₁₂H₇N₃O₂S
MW	257.27
Appearance	Pink to reddish Solid
Purity	98% by HPLC
Solubility	DMSO ( 1 mM)
Melting Point	243.03 °C
Storage Temp	-20°C
Therapeutic Area	Pulmonary Disorders
Use	A phosphoinositide 3-kinase-gamma inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis

Additional Information

MDL Number	MFCD11100415
ChemACX	X1600344-0
InChI	InChI=1S/C12H7N3O2S/c16-11-10(18-12(17)15-11)6-7-1-2-8-9(5-7)14-4-3-13-8/h1-6H,(H,15,16,17)/b10-6-
SMILES	c1cc2c(cc1/C=C3/C(=O)NC(=O)S3)nccn2

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