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PDGFR Tyrosine Kinase Inhibitor V

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产品名称: PDGFR Tyrosine Kinase Inhibitor V
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简单介绍

CAS:347155-76-4Formula:C26H23N3O43H2OMW:527.6Appearance:Off-WhiteSolidPurity:95%


PDGFR Tyrosine Kinase Inhibitor V  的详细介绍
A cell-permeable quinolinyl-thiourea compound that acts as a potent, ATP-competitive, and reversivle inhibitor of PDGFR. Inhibits c-kit receptor only at much highter concentrations. Shown to potently inhibit neointima formation in a rat carotid artery baloon injury model in vivo.

Additional Information

Product #P-1689
CAS #347155-76-4
Chemical NameN-(4-((6,7-DIMETHOXY-4-QUINOYL)OXY)PHENYL)-N'-(2-METHYLBENZOYL)THIOUREA
FormulaC26H23N3O43H2O
MW527.6
AppearanceOff-White Solid
Purity95%
SolubilityDMSO
Storage Temp+2°C to +8°C
UseA cell-permeable quinolinyl-thiourea compound that acts as a potent, ATP-competitive, and reversivle inhibitor of PDGFR

Additional Information

InChIInChI=1S/C26H23N3O4S.3H2O/c1-16-6-4-5-7-19(16)25(30)29-26(34)28-17-8-10-18(11-9-17)33-22-12-13-27-21-15-24(32-3)23(31-2)14-20(21)22;;;/h4-15H,1-3H3,(H2,28,29,30,34);3*1H2
SMILESCC1=CC=CC=C1C(=O)NC(=S)NC2=CC=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC.O.O.O
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