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AGScientific
PD 174265
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产品名称:
PD 174265
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简单介绍
CAS:216163-53-0Formula:C17H15BrN4OMW:371.2Appearance:YellowSolidPurity:98%
PD 174265
的详细介绍
A potent, cell-permeable reversible, and selective inhibitor of EGF receptor (EGFR)tyrosine kinase activity (IC=0.45 nM). The reversible nature of this compound makes it a less effective antitumor agent than PD 168393
Additional Information
Synonyms
4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline
Product #
P-1647
CAS #
216163-53-0
Chemical Name
4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline
Formula
C
17
H
15
BrN
4
O
MW
371.2
Appearance
Yellow Solid
Purity
98%
Solubility
Soluble in DMSO
Storage Temp
-20°C
Use
PD 174265 is a potent, cell-permeable, reversible, and selective inhibitor of EGFR
Additional Information
MDL Number
MFCD02179208
ChemACX
X4983431-3
InChI
InChI=1S/C17H15BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h3-10H,2H2,1H3,(H,21,23)(H,19,20,22)
SMILES
CCC(=O)Nc1ccc2c(c1)c(ncn2)Nc3cccc(c3)Br
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