PD 169316

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产品名称: PD 169316

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简单介绍

CAS:152121-53-4Formula:C20H13FN4O2MW:360.3Appearance:YellowSolidPurity:98%

PD 169316 的详细介绍

Potent, cell Permeable and selective inhibitor of p38 (SAPK2a).

Synonyms	4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
Product #	P-1185
CAS #	152121-53-4
Chemical Name	4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
Formula	C₂₀H₁₃FN₄O₂
MW	360.3
Appearance	Yellow Solid
Purity	98%
Solubility	DMSO (10 mg/ml)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	The p38 MAPK inhibitor, PD169316, inhibits transforming growth factor beta-induced Smad signaling in human ovarian cancer

MDL Number	MFCD12405019
ChemACX	X1498184-9
InChI	InChI=1S/C20H13FN4O2/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(8-4-15)25(26)27/h1-12H,(H,23,24)
SMILES	c1cc(ccc1c2[nH]c(c(n2)c3ccc(cc3)F)c4ccncc4)[N+](=O)[O-]

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