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PD 156273
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产品名称:
PD 156273
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简单介绍
Formula:C15H14BrN5MW:344.2Appearance:YellowSolidPurity:95%
PD 156273
的详细介绍
A potent inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC=0.69 nM). Also inhibits the growth of primary human tumor cell cultures.
Additional Information
Synonyms
6-Amino-4-[(3-bromophenyl)amino]-7-(methylamino)quinazoline
Product #
P-1651
Chemical Name
6-Amino-4-[(3-bromophenyl)amino]-7-(methylamino)quinazoline
Formula
C
15
H
14
BrN
5
MW
344.2
Appearance
Yellow Solid
Purity
95%
Solubility
Soluble in DMSO
Storage Temp
-20°C
Therapeutic Area
Oncological Disorders
Use
PD 156273 is a potent inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor use in cancer
Additional Information
MDL Number
MFCD02179206
InChI
InChI=1S/C15H14BrN5/c1-18-14-7-13-11(6-12(14)17)15(20-8-19-13)21-10-4-2-3-9(16)5-10/h2-8,18H,17H2,1H3,(H,19,20,21)
SMILES
CNc1cc2c(cc1N)c(ncn2)Nc3cccc(c3)Br
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