Paxilline, Penicillium paxilli

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产品名称: Paxilline, Penicillium paxilli

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简单介绍

CAS:57186-25-1Formula:C27H33O4MW:435.6Appearance:LyophilizedSolidPurity:97%

Paxilline, Penicillium paxilli 的详细介绍

Potent inhibitor of Ca activated K(maxi K) channel.Carbon monoxide activates KCa channels in newborn arteriole smooth muscle cells by increasing apparent Ca2+ sensitivity. Acidosis Dilates Brain Parenchymal Arterioles by Conversion of Calcium Waves to Sparks to Activate BK Channels.

Additional Information

Product #	P-1029
CAS #	57186-25-1
Chemical Name	(2R,4BS,6AS,12BS,12CR,14AS)-4B-HYDROXY-2-(1-HYDROXY-1-METHYLETHYL)-12B,12C-DIMETHYL-5,6,6A,7,12,12B,12C,13,14,14A-DECAHYDRO-2H-CHROMENO[5',6':6,7]INDENO[1,2-B]INDOL-3(4BH)-ONE
Formula	C₂₇H₃₃O₄
MW	435.6
Appearance	Lyophilized Solid
Purity	97%
Solubility	Soluble in DMSO
Melting Point	283-285 ‚ºC
Storage Temp	-20°C
Use	Paxilline is a toxic, tremorgenic indole alkaloid produced by Penicillium paxilli

Additional Information

MDL Number	MFCD00083464
ChemACX	X3470122-3
InChI	InChI=1S/C27H33NO4/c1-24(2,30)23-20(29)14-18-21(32-23)10-11-25(3)26(4)15(9-12-27(18,25)31)13-17-16-7-5-6-8-19(16)28-22(17)26/h5-8,14-15,21,23,28,30-31H,9-13H2,1-4H3/t15-,21-,23-,25+,26+,27+/m0/s1
SMILES	C[C@]12CC[C@H]3C(=CC(=O)[C@H](O3)C(C)(C)O)[C@@]1(CC[C@@H]4[C@@]2(c5c(c6ccccc6[nH]5)C4)C)O

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