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Pamidronate disodium
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产品名称:
Pamidronate disodium
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简单介绍
CAS:57248-88-1Formula:C3H9NO7P2Na2MW:279.03Appearance:WhiteSolidPurity:98%
Pamidronate disodium
的详细介绍
A bisphosphonate compound that inhibits bone resorption, the natural, ongoing process of bone being destroyed by osteoclasts. Also inhibits farnesyl diphosphate synthase (IC= 200 nM).
Additional Information
Synonyms
3-Amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid, disodium salt
Product #
P-2379
CAS #
57248-88-1
Chemical Name
3-Amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid, disodium salt
Formula
C
3
H
9
NO
7
P
2
Na
2
MW
279.03
Appearance
White Solid
Purity
98%
Solubility
Soluble in H
2
O (~ 25 mg/ml)
Melting Point
300 °C
Storage Temp
-20°C
Therapeutic Area
Oncological Disorders
Use
A farnesyl diphosphate synthase inhibitor
Additional Information
MDL Number
MFCD00867072
ChemACX
X1402510-8
InChI
InChI=1S/C3H11NO7P2.2Na/c4-2-1-3(5,12(6,7)8)13(9,10)11;;/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11);;/q;2*+1/p-2
SMILES
C(CN)C(O)(P(=O)(O)O)P(=O)([O-])[O-].[Na+].[Na+]
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