Paclitaxel (Taxol), Taxus brevifolia

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产品名称: Paclitaxel (Taxol), Taxus brevifolia

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简单介绍

CAS:33069-62-4Formula:C47H51NO14MW:853.9Appearance:WhiteCrystallinePowderPurity:98%

Paclitaxel (Taxol), Taxus brevifolia 的详细介绍

Anti-tumor agent isolated from the bark of the yew tree.Attached is a published reference from researchers who have used our paclitaxel product.Tectorigenin sensitizes paclitaxel-resistant human ovarian cancer cells through downregulation of the Akt and NFB pathway.Weekly paclitaxel has limited activity in esophageal cancer. The median survival, modest activity, and tolerance of therapy indicate that weekly paclitaxel may be an option in patients unable to tolerate combination chemotherapy. .Paclitaxel Enhances TF Protein Expression and Surface Activity.Paclitaxel Enhances Thrombin-Induced Endothelial Tissue Factor Expression via c-Jun Terminal NH.

Additional Information

Synonyms	Taxol, Baccatin III N-benzyl-phenylisoserine ester
Product #	P-1027
CAS #	33069-62-4
Chemical Name	Baccatin III N-benzyl-β-phenylisoserine ester
Formula	C₄₇H₅₁NO₁₄
MW	853.9
Appearance	White Crystalline Powder
Purity	98%
Solubility	DMSO
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	An antineoplastic and apoptosis inducing agent

Additional Information

Merck Index	12.7117.1996
MDL Number	MFCD00869953
ChemACX	X1009807-6
InChI	InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](c5ccccc5)NC(=O)c6ccccc6)O)O)OC(=O)c7ccccc7)(CO4)OC(=O)C)O)C)OC(=O)C

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