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Ophiobolin C

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产品名称: Ophiobolin C
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简单介绍

CAS:19022-51-6Formula:C25H38O3MW:386.6Appearance:WhitesolidPurity:>98%byHPLC


Ophiobolin C  的详细介绍
*Please inquire the availability for this product. Ophiobolin C is a member of the ophiobolin class of phytotoxic metabolites produced by many species of the genus Bipolaris. Ophiobolin C inhibits human CCR5 binding to the envelope protein gp120 and CD4 that mediates HIV-1 entry into cells. Blockade of this binding was considered by scientists at Merck as a potential new mode of action for the treatment of HIV-1 infection.

Additional Information

SynonymsZizanin A
Product #O-2555
CAS #19022-51-6
FormulaC25H38O3
MW386.6
AppearanceWhite solid
Purity>98% by HPLC
SolubilitySoluble in ethanol, methanol, DMF or DMSO Limited water solubility
Storage Temp-20°C
UseOphiobolin C is a member of the ophiobolin class of phytotoxic metabolites produced by many species of the genus Bipolaris

Additional Information

MDL NumberMFCD09752745
InChIInChI=1S/C25H38O3/c1-16(2)7-6-8-17(3)19-11-12-24(4)13-21-23(22(27)14-25(21,5)28)18(15-26)9-10-20(19)24/h7,9,15,17,19-21,23,28H,6,8,10-14H2,1-5H3/b18-9-/t17-,19?,20?,21-,23+,24+,25+/m0/s1
SMILESC/C(C)=C\CC[C@H](C)C1CC[C@]2(C)C[C@@H]3[C@](C)(O)CC(=O)[C@@H]3C(=C\CC12)/C=O
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