Oligomycin | CAS [14104-19-9] | Antibiotics | Inhibits membrane bound mitochond

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产品名称: Oligomycin | CAS [14104-19-9] | Antibiotics | Inhibits membrane bound mitochond

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简单介绍

CAS:1404-19-9Formula:C45H74O11MW:791.1Appearance:WhitepowderPurity:97%(TLC)

Oligomycin | CAS [14104-19-9] | Antibiotics | Inhibits membrane bound mitochond 的详细介绍

Oligomycin Complex of Oligomycin A, B and C. This antibiotic inhibits membrane bound mitochondrial ATPase. It is isolated from Streptomyces diastatochromogenes. Inhibits mitochondrial F1F0 ATP synthase. A useful tool for decreasing cellular ATP levels. Induces autophagy. Stimulates lysosome acidification. Protects against ischemic kidney in male rats.

Additional Information

Product #	O-1060
CAS #	1404-19-9
Formula	C₄₅H₇₄O₁₁
MW	791.1
Appearance	White powder
Purity	97% (TLC)
Solubility	May be dissolved in DMSO (300 mg/ml); or ethanol (200 mg/ml).
Melting Point	118-121‚°C
Storage Temp	Store desiccated at -20°C.
Therapeutic Area	Infectious Diseases
Use	Oligomycins are macrolides created by Streptomyces use as antibiotics.

Additional Information

Merck Index	13.6902.2001
MDL Number	MFCD01779388
ChemACX	X4634181-1
InChI	InChI=1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13-,17-15-,21-18-
SMILES	CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C

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