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NVP-AUY922

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产品名称: NVP-AUY922
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简单介绍

CAS:747412-49-3Formula:C26H31N3O6MW:465.54Appearance:Whitetooff-whiteSolidPurity:99%


NVP-AUY922  的详细介绍

A Hsp90 inhibitor. NVP-AUY922 has excellent potency against Hsp90 in a fluorescence polarization binding assay with an ICof 21 nmol/L against theisoform and of 13 nmol/L for the isoform.

Additional Information

Synonyms5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
Product #N-2368
CAS #747412-49-3
Chemical Name5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
FormulaC26H31N3O6
MW465.54
AppearanceWhite to off-white Solid
Purity99%
SolubilityDMSO (10 mM)
Melting Point178-190 °C
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseA highly potent HSP90 inhibitor to HSP90α and HSP90β in cancer

Additional Information

MDL NumberMFCD14635361
ChemACXX1812371-2
InChIInChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32)
SMILESCCNC(=O)c1c(c(on1)c2cc(c(cc2O)O)C(C)C)c3ccc(cc3)CN4CCOCC4
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