Novobiocin

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产品名称: Novobiocin

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简单介绍

CAS:303-81-1Formula:C31H36N2O11MW:612.6Appearance:PaleyellowsolidPurity:>95%byHPLC

Novobiocin 的详细介绍

*Please inquire the availability for this product. Novobiocin is an aminocoumarin antibiotic isolated from a number of species of Streptomyces. Novobiocin exhibits broad spectrum Gram positive antibiotic activity and was used clinically. Novobiocin is a potent inhibitor of bacterial DNA gyrase and a competitive inhibitor of the ATPase reaction catalysed by GyrB.

Additional Information

Synonyms	Albamycin, Vulcamycin, PA 93, WS 6629, Griseoflavin, S 800.
Product #	N-2613
CAS #	303-81-1
Formula	C₃₁H₃₆N₂O₁₁
MW	612.6
Appearance	Pale yellow solid
Purity	>95% by HPLC
Solubility	Soluble in ethanol, methanol, DMF, and DMSO,Limited water solubility
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Novobiocin exhibits broad spectrum Gram positive antibiotic activity

Additional Information

MDL Number	MFCD00072100
InChI	InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1
SMILES	Cc1c(ccc2c1oc(=O)c(c2O)NC(=O)c3ccc(c(c3)CC=C(C)C)O)O[C@H]4[C@@H]([C@@H]([C@H](C(O4)(C)C)OC)OC(=O)N)O

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