MS-1020

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产品名称: MS-1020

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简单介绍

Formula:C21H18N2O3MW:346.38Appearance:Whitetooff-whiteSolidPurity:95%byNMR

MS-1020 的详细介绍

Cell-permeable. A selective JAK3 inhibitor. Blocks STAT signaling and induces apoptosis via down-regulation of anti-apoptotic gene expression.

Synonyms	1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide
Product #	M-2357
Chemical Name	1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide
Formula	C₂₁H₁₈N₂O₃
MW	346.38
Appearance	White to off-white Solid
Purity	95% by NMR
Solubility	Soluble in DMSO (5 mg/ml)
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A selective JAK3 inhibitor use in cancer

MDL Number	MFCD21363377
ChemACX	X4471856-9
InChI	InChI=1S/C21H18N2O3/c24-15-6-8-19-18(11-15)14(12-23-19)9-10-22-21(26)17-7-5-13-3-1-2-4-16(13)20(17)25/h1-8,11-12,23-25H,9-10H2,(H,22,26)
SMILES	c1ccc2c(c1)ccc(c2O)C(=O)NCCc3c[nH]c4c3cc(cc4)O

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