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Monazomycin

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产品名称: Monazomycin
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简单介绍

CAS:11006-31-8Formula:C72H133NO22MW:1364.8Appearance:WhitetofawnsolidPurity:>95%byHPLC


Monazomycin  的详细介绍
*Please inquire the availability for this product. Monazomycin is a macrocylic polyol lactone isolated from several species of Streptoverticillium, first reported in 1963. Monazomycin is active against Gram positive bacteria with weak Gram negative activity. In solution, monazomycin exists as hydrophilic clusters which, when adsorbed onto a lipid bilayer, can induce channel formation. Monazomycin is an important bioprobe for understanding membrane channels.

Additional Information

Product #M-2605
CAS #11006-31-8
FormulaC72H133NO22
MW1364.8
AppearanceWhite to fawn solid
Purity>95% by HPLC
Storage Temp-20°C
Therapeutic AreaInfectious Diseases
UseMonazomycin is a macrocyclic polyol lactone antibiotic active against Gram positive bacteria with weak Gram negative activity

Additional Information

MDL NumberMFCD01714647
InChIInChI=1S/C72H133NO22/c1-39-22-19-20-25-55(79)46(8)54(78)24-17-15-18-26-62(84)95-71(42(4)23-16-13-14-21-31-73)50(12)59(83)37-53(77)36-58(82)48(10)66(88)47(9)56(80)34-51(75)29-27-40(2)63(85)41(3)28-30-52(76)35-57(81)49(11)67(89)60(33-45(7)65(87)44(6)32-43(5)64(39)86)93-72-70(92)69(91)68(90)61(38-74)94-72/h19,22,28,30,32-33,39-42,44,46-61,63-72,74-83,85-92H,13-18,20-21,23-27,29,31,34-38,73H2,1-12H3/b22-19-,30-28-,43-32-,45-33-/t39?,40?,41?,42?,44?,46?,47?,48?,49?,50?,51?,52?,53?,54?,55?,56?,57?,58?,59?,60?,61-,63?,64?,65?,66?,67?,68-,69+,70+,71?,72+/m1/s1
SMILESCC1CCC(CC(C(C(C(C(CC(CC(C(C(OC(=O)CCCCCC(C(C(CC/C=C\C(C(/C(=C\C(C(/C(=C\C(C(C(C(CC(/C=C\C(C1O)C)O)O)C)O)O[C@@H]2[C@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)/C)O)C)/C)O)C)O)C)O)C(C)CCCCCCN)C)O)O)O)C)O)C)O)O
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