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Mizoribine
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产品名称:
Mizoribine
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简单介绍
CAS:50924-49-7Formula:C9H12N3O6MW:259.22Appearance:Solid
Mizoribine
的详细介绍
Mizoribine, immunosuppressant that is believed to achieve immunosuppression by inhibiting DNA synthesis in the S phase of the cell cycle thus preventing the division and proliferation of lymphocytes. Recently it has been shown to have an effect which may affect Heat Shock Protein 60.
Additional Information
Product #
M-1217
CAS #
50924-49-7
Chemical Name
5-HYDROXY-1-BETA-D-RIBOFURANOSYL-1H-IMIDAZOLE-4-CARBOXAMIDE
Formula
C
9
H
12
N
3
O
6
MW
259.22
Appearance
Solid
Solubility
Soluble in water (52 mg/ml), DMSO (52 mg/ml), ethanol (<1 mg/ml), and methanol.
Storage Temp
-20°C
Therapeutic Area
Autoimmune Diseases
Use
An imidazole nucleoside immunosuppressant agent used to treat lupus erythematosus, renal transplantation
Additional Information
MDL Number
MFCD00057221
ChemACX
X1064145-9
InChI
InChI=1S/C9H13N3O6/c10-7(16)4-8(17)12(2-11-4)9-6(15)5(14)3(1-13)18-9/h2-3,5-6,9,13-15,17H,1H2,(H2,10,16)/t3-,5-,6-,9-/m1/s1
SMILES
c1nc(c(n1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)N
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