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Mitoxantrone

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产品名称: Mitoxantrone
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简单介绍

CAS:65271-80-9Formula:C22H28N4O6MW:444.48Appearance:DarkbluesoildPurity:98%


Mitoxantrone  的详细介绍
An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells.

Additional Information

Synonyms1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione
Product #M-2381
CAS #65271-80-9
Chemical Name1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione
FormulaC22H28N4O6
MW444.48
AppearanceDark blue soild
Purity98%
SolubilityDMSO
Melting Point170-174 °C
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseA DNA intercalating drug that inhibits DNA synthesis and is used as an anti-cancer agent.

Additional Information

MDL NumberMFCD00242942
ChemACXX1012957-6
InChIInChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2
SMILESc1cc(c2c(c1NCCNCCO)C(=O)c3c(ccc(c3C2=O)O)O)NCCNCCO
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