Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore

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产品名称: Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore

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简单介绍

Formula:C35H31BrN3O8PMW:732.51Appearance:PaleyellowsolidPurity:98%byTLCNMR(Conforms)

Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore 的详细介绍

Mito-Photo-DNP is a mitochondria-targeted, photo-activated protonophore. This novel tool consists of three structural units, a caged protonophore, a photocleavable linker coupled to a triphenylphosphonium moiety which confers selective uptake by the mitochondria. Cells are treated with Mito-Photo-DNP at 200 nM and irradiated with UV light at 355 nm. Mito-Photo-DNP can be employed for selective uncoupling of either individual or a small number of mitochondria within a cell when used with fluorescence imaging.

Application:

Used for research studies, to manipulate mitochondrial function;
To release bioactive molecules, pharmacophores, or toxins to mitochondria with tissue, cell, or mitochondrion specificity.

Additional Information

Product #	M-3325
Chemical Name	(4-(3-((2,4-Dinitrophenoxy)methyl)-4-nitrophenoxy)butyl)triphenylphosphonium
Formula	C₃₅H₃₁BrN₃O₈P
MW	732.51
Appearance	Pale yellow solid
Purity	98% by TLC NMR (Conforms)
Solubility	Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 30 mg/ml).
Storage Temp	-20°C
Use	Used to manipulate mitochondrial function; to release bioactive molecules, pharmacophores, or toxins to mitochondria with tissue, cell, or mitochondrion specificity.

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