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Minocycline hydrochloride

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产品名称: Minocycline hydrochloride
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简单介绍

CAS:13614-98-7Formula:C23H28ClN3O7MW:493.9Appearance:YellowtoorangesolidPurity:>98%byHPLC


Minocycline hydrochloride  的详细介绍
*Please inquire the availability for this product. Minocycline hydrochloride is a salt prepared from minocycline, taking advantage of the two basic dimethylamino groups which protonate and readily form a salt from hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, minocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

Additional Information

SynonymsKlinomycin, Minocycline chloride, Minomycin, NSC 141993
Product #M-2599
CAS #13614-98-7
FormulaC23H28ClN3O7
MW493.9
AppearanceYellow to orange solid
Purity>98% by HPLC
SolubilitySoluble in DMSO (7 mg/ml), water (50 mg/ml), methanol, and aqueous solutions of alkali hydroxides and carbonates
Melting Point193-226 °C
Storage Temp4°C
Therapeutic AreaInfectious Diseases
UseMinocycline is used to treat infections, such as urinary tract infections, acne and chlamydia

Additional Information

MDL NumberMFCD00083669
InChIInChI=1S/C23H27N3O7.ClH/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28;/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32);1H/t9-,11-,17?,23-;/m0./s1
SMILESCN(C)c1ccc(c2c1C[C@H]3C[C@H]4C(C(=C(C(=O)[C@]4(C(=C3C2=O)O)O)C(=O)N)O)N(C)C)O.Cl
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