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Minocycline hydrochloride
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产品名称:
Minocycline hydrochloride
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简单介绍
CAS:13614-98-7Formula:C23H28ClN3O7MW:493.9Appearance:YellowtoorangesolidPurity:>98%byHPLC
Minocycline hydrochloride
的详细介绍
*Please inquire the availability for this product. Minocycline hydrochloride is a salt prepared from minocycline, taking advantage of the two basic dimethylamino groups which protonate and readily form a salt from hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, minocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
Additional Information
Synonyms
Klinomycin, Minocycline chloride, Minomycin, NSC 141993
Product #
M-2599
CAS #
13614-98-7
Formula
C23H28ClN3O7
MW
493.9
Appearance
Yellow to orange solid
Purity
>98% by HPLC
Solubility
Soluble in DMSO (7 mg/ml), water (50 mg/ml), methanol, and aqueous solutions of alkali hydroxides and carbonates
Melting Point
193-226 °C
Storage Temp
4°C
Therapeutic Area
Infectious Diseases
Use
Minocycline is used to treat infections, such as urinary tract infections, acne and chlamydia
Additional Information
MDL Number
MFCD00083669
InChI
InChI=1S/C23H27N3O7.ClH/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28;/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32);1H/t9-,11-,17?,23-;/m0./s1
SMILES
CN(C)c1ccc(c2c1C[C@H]3C[C@H]4C(C(=C(C(=O)[C@]4(C(=C3C2=O)O)O)C(=O)N)O)N(C)C)O.Cl
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