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Minocycline

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产品名称: Minocycline
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简单介绍

CAS:10118-90-8Formula:C23H27N3O7MW:457.5Appearance:YellowtoorangesolidPurity:>98%byHPLC


Minocycline  的详细介绍
*Please inquire the availability for this product. Minocycline is a semi-synthetic tetracycline prepared by sequential hydrogenolysis, nitration and reductive methylation. Minocycline, together with doxycycline, is regarded as a ‘third generation’ tetracycline largely replacing the natural products and pro-drugs produced in the early 1950s for mainstream antibiotic applications. Like all tetracyclines, minocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. Minocycline has been extensively cited in the literature with over 5,000 references.

Additional Information

Synonyms7-Dimethylamino-6-demethyl-6-deoxytetracycline, CL 59806, Minocyclin
Product #M-2597
CAS #10118-90-8
FormulaC23H27N3O7
MW457.5
AppearanceYellow to orange solid
Purity>98% by HPLC
Therapeutic AreaInfectious Diseases
UseMinocycline is used to treat infections, such as urinary tract infections, acne and chlamydia

Additional Information

MDL NumberMFCD00072105
InChIInChI=1S/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27,29-30,33H,7-8H2,1-4H3,(H2,24,32)/t9-,11-,17-,23-/m0/s1
SMILESCN(C)c1ccc(c2c1C[C@H]3C[C@H]4[C@@H](C(=C(C(=O)[C@]4(C(=C3C2=O)O)O)C(=O)N)O)N(C)C)O
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