Meclocycline

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产品名称: Meclocycline

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简单介绍

CAS:2013-58-3Formula:C22H21ClN2O8MW:476.9Appearance:YellowtoorangesolidPurity:>98%byHPLC

Meclocycline 的详细介绍

*Please inquire the availability for this product. Meclocycline is a semi-synthetic tetracycline prepared by dehydration of the 6-hydroxy group of chlortetracycline to yield an exocyclic 6-methylene. Meclocycline is a close structural analogue of methacycline. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. Meclocycline has been extensively cited in the literature with over 400 references.

Additional Information

Synonyms	7-Chloro-6-methylene-oxytetracycline, GS 2989, NCS 78502
Product #	M-2559
CAS #	2013-58-3
Formula	C₂₂H₂₁ClN₂O₈
MW	476.9
Appearance	Yellow to orange solid
Purity	>98% by HPLC
Solubility	Soluble in ethanol, methanol, DMF, DMSO Limited water solubility
Melting Point	339.97 °C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Meclocycline is a tetracycline antibiotic used topically for skin infections

Additional Information

MDL Number	MFCD00864872
InChI	InChI=1S/C22H21ClN2O8/c1-6-9-7(23)4-5-8(26)11(9)16(27)12-10(6)17(28)14-15(25(2)3)18(29)13(21(24)32)20(31)22(14,33)19(12)30/h4-5,10,14-15,17,26,28-30,33H,1H2,2-3H3,(H2,24,32)/t10-,14-,15+,17+,22+/m1/s1
SMILES	CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)c4c(ccc(c4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O)Cl)O

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