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LY-364947

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产品名称: LY-364947
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简单介绍

CAS:396129-53-6Formula:C17H12N4MW:272.31Appearance:Solid


LY-364947  的详细介绍
ALK5 kinase inhibitor

Additional Information

Product #L-2489
CAS #396129-53-6
FormulaC17H12N4
MW272.31
AppearanceSolid
SolubilitySoluble in DMSO (100 mM), water (<1 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), DMF (~0.1 mg/ml), and 1:1 DMF:PBS (pH 7.2)
Melting Point230 °C
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseLY 364947 is a diheteroaryl-substituted pyrazole compound used as a selective, ATP-competitive inhibitor of TGF-βRI (TGF-β Receptor I kinase)

Additional Information

MDL NumberMFCD00800758
ChemACXX1193484-8
InChIInChI=1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21)
SMILESc1ccc2c(c1)c(ccn2)c3c[nH]nc3c4ccccn4
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