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Lipstatin
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产品名称:
Lipstatin
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简单介绍
CAS:96829-59-3Formula:C29H49NO5MW:491.7Appearance:PaleyellowoilPurity:>95%byHPLC
Lipstatin
的详细介绍
*Please inquire the availability for this product. Lipstatin is a potent irreversible inhibitor of pancreatic lipase, produced by Streptomyces toxytricini and first reported in 1987. In vivo, lipstatin acts to block the absorption of triglycerides while allowing fatty acid absorption. The tetrahydro analogue of lipstatin, orlistat, although less potent, was developed for the treatment of obesity.
Additional Information
Product #
L-2557
CAS #
96829-59-3
Formula
C
29
H
49
NO
5
MW
491.7
Appearance
Pale yellow oil
Purity
>95% by HPLC
Therapeutic Area
Metabolic Disorders
Use
Lipstatin, a potent inhibitor of the pancreas lipase useful in the treatment of obesity
Additional Information
MDL Number
MFCD09838128
InChI
InChI=1S/C29H49NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h12-13,15-16,22-27H,5-11,14,17-21H2,1-4H3,(H,30,31)/b13-12-,16-15-/t24-,25-,26-,27-/m0/s1
SMILES
O=C(O[C@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)C\C=C/C\C=C/CCCCC)[C@@H](NC=O)CC(C)C
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