Lincomycin

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产品名称: Lincomycin

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简单介绍

CAS:154-21-2Formula:C18H34N2O6SMW:406.5Appearance:WhitesolidPurity:>99%byHPLC

Lincomycin 的详细介绍

*Please inquire the availability for this product. Lincomycin is a polar, water soluble, broad spectrum antibiotic first isolated from Streptomyces licolnensis by researchers at Upjohn in 1962. Lincomycin was the first of a unique structural class, the lincosamides, containing a rare amino acid, 4-propyl-N-methylproline, coupled to an equally rare aminomethylthio-octopyranoside sugar. Lincomycin and semi-synthetic analogues are often incorrectly considered to be aminoglycosides but share little or no structural similarity. Lincomycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Lincomycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Lincomycin has been extensively studied with over 7,000 literature citations.

Additional Information

Synonyms	Linocin, Lincolnensin, U 10149, Jiemycin
Product #	L-2553
CAS #	154-21-2
Formula	C₁₈H₃₄N₂O₆S
MW	406.5
Appearance	White solid
Purity	>99% by HPLC
Solubility	Soluble in ethanol, methanol, DMF, DMSO, and water
Melting Point	262.24 °C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Lincomycin broad spectrum antibiotic with activity against anaerobic bacteria and protozoans

Additional Information

MDL Number	MFCD00864895
InChI	InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1
SMILES	CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O

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