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Lexithromycin

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产品名称: Lexithromycin
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简单介绍

CAS:53066-26-5Formula:C38H70N2O13MW:763Appearance:WhitesolidPurity:>98%byHPLC


Lexithromycin  的详细介绍
*Please inquire the availability for this product. Lexithromycin is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. The structural change improves the pH stability profile and hydrophobicity of lexithromycin for better in vivo absorption. This same rationale was used to greater effect with roxithromycin and, as a result, lexithromycin was quickly superseded and has not been not extensively studied. Like all erythromycins, lexithromycin shows broad spectrum antibacterial activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

Additional Information

SynonymsErythromycin A 9-methoxime, Wy 48314
Product #L-2551
CAS #53066-26-5
FormulaC38H70N2O13
MW763
AppearanceWhite solid
Purity>98% by HPLC
Storage Temp-20°C
Therapeutic AreaInfectious Diseases
Uselexithromycin shows broad spectrum antibacterial activity

Additional Information

MDL NumberMFCD00864895
InChIInChI=1S/C38H70N2O13/c1-15-26-38(10,46)31(42)21(4)28(39-48-14)19(2)17-36(8,45)33(53-35-29(41)25(40(11)12)16-20(3)49-35)22(5)30(23(6)34(44)51-26)52-27-18-37(9,47-13)32(43)24(7)50-27/h19-27,29-33,35,41-43,45-46H,15-18H2,1-14H3/b39-28+/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
SMILESCC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
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