Lestaurtinib

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产品名称: Lestaurtinib

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简单介绍

CAS:111358-88-4Formula:C26H21N3O4MW:439.46Appearance:WhitepowderPurity:≥98%byHPLC

Lestaurtinib 的详细介绍

An indolocarbazole derivative with antineoplastic properties. Acts as a potent inhibitor of several tyrosine kinases including FLT3, JAK2, and TrkA with IC₅₀ values of 3, 1, and <25 nM, respectively. It suppresses JAK2/STAT5 signaling and is effective against myeloproliferative disorders in vivo.

Additional Information

Product #	L-2374
CAS #	111358-88-4
Chemical Name	CEP-701; KT-5555; SPM-924
Formula	C₂₆H₂₁N₃O₄
MW	439.46
Appearance	White powder
Purity	≥98% by HPLC
Solubility	DMSO (100 mg/ml) and Ethanol (20 mg/ml)
Storage Temp	-20°C

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