L-156602

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产品名称: L-156602

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简单介绍

CAS:125528-51-5Formula:C38H64N8O13MW:840.5Appearance:WhitesolidoffwhitelighttanPurity:>95%byHPLC

L-156602 的详细介绍

*Please inquire the availability for this product. L 156602 is a cyclic hexapeptide isolated from a strain of Streptomyces by researchers at Merck USA and reported in 1991. L 156602 belongs to the aurantimycin class and, like other members, is active against Gram positive bacteria. L 156602 was foremost discovered as a competitive binding inhibitor of the inflammatory peptide, C5a, to cell surface receptors on macrophages. In vivo, L 156602 profoundly suppresses footpad edema induced by concanavalin A and completely suppresses the infiltration of mononuclear leukocytes and neutrophils into the site of inflammation.

Additional Information

Synonyms	Antibiotic L 16602
Product #	L-2519
CAS #	125528-51-5
Formula	C₃₈H₆₄N₈O₁₃
MW	840.5
Appearance	White solid off white light tan
Purity	>95% by HPLC
Therapeutic Area	Infectious Diseases
Use	L 156602 is antibiotic belongs to the aurantimycin class and active against Gram positive bacteria

Additional Information

InChI	InChI=1S/C38H64N8O13/c1-9-21(4)18-25-14-15-38(55,59-24(25)7)37(8,54)36(53)42-29-30(20(2)3)58-35(52)23(6)46(57)32(49)26-12-10-16-40-43(26)28(47)19-39-31(48)22(5)45(56)33(50)27-13-11-17-41-44(27)34(29)51/h20-27,29-30,40-41,54-57H,9-19H2,1-8H3,(H,39,48)(H,42,53)
SMILES	CCC(C)CC1CCC(OC1C)(C(C)(C(=O)NC2C(OC(=O)C(N(C(=O)C3CCCNN3C(=O)CNC(=O)C(N(C(=O)C4CCCNN4C2=O)O)C)O)C)C(C)C)O)O

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