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KN-93, Water-Soluble

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产品名称: KN-93, Water-Soluble
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简单介绍

Formula:C26H29CIN2O4SH3PO4MW:599Appearance:WhiteSolidPurity:95%


KN-93, Water-Soluble  的详细介绍

 A water-soluble form of the CaM kinase II inhibitor KN-93. Inhibits glucose-induced and forskolin-stimulated insulin release from isolated pancreatic islets of Langerhans. Has no significant effect on protein kinase A activity. Induces G cell cycle arrest and apoptosis in NIH 3T3 cells.

Additional Information

Product #K-1092
FormulaC26H29CIN2O4S H3PO4
MW599
AppearanceWhite Solid
Purity95%
SolubilitySoluble in H2O (5 mg/ml)
Storage Temp+4°C
Therapeutic AreaCardiological Disorders
UseKN-93 potently inhibited myocardial CaM kinase activity

Additional Information

MDL NumberMFCD03788201
ChemACXX7633487-7
InChIInChI=1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+;
SMILESCN(C/C=C/c1ccc(cc1)Cl)Cc2ccccc2N(CCO)S(=O)(=O)c3ccc(cc3)OC.OP(=O)(O)O
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