JNJ 16259685

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产品名称: JNJ 16259685

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简单介绍

CAS:409345-29-5Formula:C20H23NO3MW:325.4Appearance:WhitetoOff-whitePurity:98%

JNJ 16259685 的详细介绍

Potent, non-competitive mGluR1 antagonist (K=-0.34 nM). Inhibits glutamate-induced Ca2+ response at the human mGluR1 (IC=0.55 nM). Selective over mGluR5 (400-fold).

Additional Information

Product #	J-1100
CAS #	409345-29-5
Chemical Name	(3,4-DIHYDRO-2H-PYRANO[2,3-B]QUINOLIN-7-YL)-(CIS-4-METHOXYCYCLOHEXYL)-METHANONE
Formula	C₂₀H₂₃NO₃
MW	325.4
Appearance	White to Off-white
Purity	98%
Solubility	Soluble in DMSO, or 100% Ethanol.
Storage Temp	+4°C
Use	JNJ 16259685 is a sub-nanomolar potent, non-competitive mGluR-1 antagonist

Additional Information

MDL Number	MFCD08690525
ChemACX	X1579337-0
InChI	InChI=1S/C20H23NO3/c1-23-17-7-4-13(5-8-17)19(22)14-6-9-18-16(11-14)12-15-3-2-10-24-20(15)21-18/h6,9,11-13,17H,2-5,7-8,10H2,1H3/t13-,17+
SMILES	CO[C@H]1CC[C@H](CC1)C(=O)c2cc3c(nc4c(c3)CCCO4)cc2

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