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Janex-1

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产品名称: Janex-1
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简单介绍

CAS:202475-60-3Formula:C16H15N3O3MW:297.31Appearance:Whitetooff-whiteSolidPurity:98%byTLC


Janex-1  的详细介绍
Cell-permeable. Selectively inhibits the tyrosine kinase activity of Jak3 with an ICvalue of 78 M without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases. Also helps to induce rat bone marrow stromal cells (MSCs) to neuronal cells.

Additional Information

Synonyms4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol,WHI-P131
Product #W-2482
CAS #202475-60-3
Chemical Name4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol
FormulaC16H15N3O3
MW297.31
AppearanceWhite to off-white Solid
Purity98% by TLC
SolubilityDMSO (~50mg/ml
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseJAK3 kinase inhibitor use in cancer

Additional Information

MDL NumberMFCD01862614
ChemACXX1863890-1
InChIInChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
SMILESCOc1cc2c(cc1OC)ncnc2Nc3ccc(cc3)O
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