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AGScientific
Janex-1
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Janex-1
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简单介绍
CAS:202475-60-3Formula:C16H15N3O3MW:297.31Appearance:Whitetooff-whiteSolidPurity:98%byTLC
Janex-1
的详细介绍
Cell-permeable. Selectively inhibits the tyrosine kinase activity of Jak3 with an ICvalue of 78 M without affecting the enzymatic activity of JAK1, JAK2, or other protein tyrosine kinases. Also helps to induce rat bone marrow stromal cells (MSCs) to neuronal cells.
Additional Information
Synonyms
4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol,WHI-P131
Product #
W-2482
CAS #
202475-60-3
Chemical Name
4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol
Formula
C
16
H
15
N
3
O
3
MW
297.31
Appearance
White to off-white Solid
Purity
98% by TLC
Solubility
DMSO (~50mg/ml
Storage Temp
-20°C
Therapeutic Area
Oncological Disorders
Use
JAK3 kinase inhibitor use in cancer
Additional Information
MDL Number
MFCD01862614
ChemACX
X1863890-1
InChI
InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
SMILES
COc1cc2c(cc1OC)ncnc2Nc3ccc(cc3)O
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