JAK Inhibitor I

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产品名称: JAK Inhibitor I

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简单介绍

CAS:457081-03-7Formula:C18H16FN3OMW:309.3Appearance:Off-WhiteSolidPurity:98%

JAK Inhibitor I 的详细介绍

A potent, cell-permeable, and ATP-competitive inhibitor of Janus protein tyrosine kinases (JAKs).

Synonyms	CMP 6, Pyridone 6, Janus-associated kinase inhibitor I, 2-(1,1- dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5- f]isoquinolin-7-one
Product #	J-1130
CAS #	457081-03-7
Chemical Name	2-(1,1- dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5- f]isoquinolin-7-one
Formula	C₁₈H₁₆FN₃O
MW	309.3
Appearance	Off-White Solid
Purity	98%
Solubility	Soluble in DMSO
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	An inhibitor of JAK1, JAK2, and JAK3

MDL Number	MFCD17019334
ChemACX	X1881054-3
InChI	InChI=1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
SMILES	CC(C)(C)c1[nH]c2c3cc[nH]c(=O)c3c4cc(ccc4c2n1)F

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