IOX 1, JMJD demethylase inhibitor

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产品名称: IOX 1, JMJD demethylase inhibitor

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简单介绍

CAS:5852-78-8Formula:C10H7NO3MW:189.17Appearance:YellowsolidPurity:98%byHPLCNMR(Conforms)

IOX 1, JMJD demethylase inhibitor 的详细介绍

IOX 1 (5852-78-8) inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC₅₀ = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. A broad spectrum 2-oxoglutarate oxygenase inhibitor, IOX 1 may be used to study hypoxic signaling. Cell permeable

Additional Information

Product #	I-2629
CAS #	5852-78-8
Chemical Name	8-Hydroxy-5-quinolinecarboxylic acid
Formula	C₁₀H₇N_O₃
MW	189.17
Appearance	Yellow solid
Purity	98% by HPLC NMR (Conforms)
Solubility	Soluble in DMSO (up to 20 mg/ml).
Storage Temp	RT (des.)

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