Imiquimod

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产品名称: Imiquimod

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简单介绍

CAS:99011-02-6Formula:C14H16N4MW:240.3Appearance:Whitetooff-whiteSolidPurity:95%byHPLC

Imiquimod 的详细介绍

Cell-permeable. Topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of Toll-like receptor 7 (TLR7) and subsequent activation of MyD88-dependent pathway.

Additional Information

Synonyms	1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837
Product #	I-2361
CAS #	99011-02-6
Chemical Name	1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837
Formula	C₁₄H₁₆N₄
MW	240.3
Appearance	White to off-white Solid
Purity	95% by HPLC
Solubility	Soluble in DMSO
Melting Point	292-294 °C
Storage Temp	-20°C
Use	A TLR7 activator and angiogenesis inhibitor used to treat certain diseases of the skin, including skin cancers (basal cell carcinoma, Bowen's disease,superficial squamous cell carcinoma

Additional Information

MDL Number	MFCD00866946
ChemACX	X1063616-9
InChI	InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)
SMILES	CC(C)Cn1cnc2c1c3ccccc3nc2N

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