IM-54

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产品名称: IM-54

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简单介绍

CAS:861891-50-1Formula:C19H23N3O2MW:325.4Appearance:YellowPowderPurity:98%(HPLC)

IM-54 的详细介绍

IM-54 is an indolylmaleimide derivative which, at 1M, inhibits necrotic cell death induced by H in promyelocytic leukemia HL-60 cells. It does not prevent etoposide-induced apoptosis and does not inhibit protein kinase C or S6 kinase 1

Additional Information

Synonyms	[2-(1H-Indol-3-yl)-3-pentylamino-maleimide]
Product #	I-1322
CAS #	861891-50-1
Chemical Name	[2-(1H-Indol-3-yl)-3-pentylamino-maleimide]
Formula	C₁₉H₂₃N₃O₂
MW	325.4
Appearance	Yellow Powder
Purity	98% (HPLC)
Solubility	Soluble in DMSO (100mg/ml), dichloomethane, 100%
Storage Temp	-20°C
Therapeutic Area	Cardiological Disorders
Use	Necrosis Inhibitor, IM-54 is a cell-permeable mono-indolylmaleimide compound that selectively blocks oxidative stress-induced necrotic cell death as potential cardioprotective agents

Additional Information

MDL Number	MFCD18382109
ChemACX	X3939492-4
InChI	InChI=1S/C19H23N3O2/c1-4-5-8-11-20-17-16(18(23)22(3)19(17)24)14-12-21(2)15-10-7-6-9-13(14)15/h6-7,9-10,12,20H,4-5,8,11H2,1-3H3
SMILES	CCCCCNC1=C(C(=O)N(C1=O)C)c2cn(c3c2cccc3)C

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