Ikarugamycin, Antiprotozoal antibiotic

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产品名称: Ikarugamycin, Antiprotozoal antibiotic

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简单介绍

CAS:36531-78-9Formula:C29H40N2O4MW:480.7

Ikarugamycin, Antiprotozoal antibiotic 的详细介绍

Antiprotozoal antibiotic found to inhibit cholesteryl ester accumulation in macrophage. Inhibitor of clathrin-coated pits (CCP) dependent endocytosis

Product #	I-1192
CAS #	36531-78-9
Chemical Name	14,17-METHENO-17H-AS-INDACENO[3,2-K][1,6]DIAZACYCLOHEPTADECINE-9,16,18(1H)-TRIONE
Formula	C₂₉H₄₀N₂O₄
MW	480.7
Solubility	Soluble in DMFA, DMSO, THF
Melting Point	228-229°C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Ikarugamycin is an antiprotozoal macrolactam antibiotic demonstrating cytostatic effects and activity against gram-positive bacteria

MDL Number	MFCD01722005
ChemACX	X1407205-2
InChI	InChI=1S/C29H38N2O4/c1-3-18-16(2)14-22-20(18)10-11-21-19-6-4-8-26(33)30-13-5-7-24-28(34)27(29(35)31-24)25(32)12-9-17(19)15-23(21)22/h4,8-12,16-24,34H,3,5-7,13-15H2,1-2H3,(H,30,33)(H,31,35)/b8-4-,12-9+/t16-,17-,18-,19+,20+,21-,22+,23+,24+/m1/s1
SMILES	CC[C@@H]1[C@@H](C[C@H]2[C@H]1C=C[C@H]3[C@@H]2C[C@@H]4[C@@H]3C/C=CC(=O)NCCC[C@H]5C(=C(C(=O)/C=C4)C(=O)N5)O)C

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