Hymeglusin (Inhibitor of HMG-CoA synthase,Scopulariopsis sp.)

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产品名称: Hymeglusin (Inhibitor of HMG-CoA synthase,Scopulariopsis sp.)

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简单介绍

CAS:9027-44-5Formula:C18H28O5MW:324.4Appearance:Whitetooff-whiteamorphousSolidPurity:95%(HPLC)

Hymeglusin (Inhibitor of HMG-CoA synthase,Scopulariopsis sp.) 的详细介绍

Specific and irreversible inhibitor of HMG-CoA synthasein vitro andin vivo. Inhibits mevalonate biosynthesis. Shows anti-microbial and anti-fungal activity.

Additional Information

Synonyms	1233A, F-244
Product #	H-1332
CAS #	9027-44-5
Chemical Name	(2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid
Formula	C₁₈H₂₈O₅
MW	324.4
Appearance	White to off-white amorphous Solid
Purity	95% (HPLC)
Solubility	Soluble in methanol, 100% ethanol, ethyl acetate or acetonitrile; insoluble in water.
Melting Point	196.60 °C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Hymeglusin is a fungal β-lactone antibiotic that inhibits HMG-CoA synthase

Additional Information

MDL Number	MFCD01940046
ChemACX	X4864521-8
InChI	InChI=1S/C18H28O5/c1-12(8-13(2)9-14(3)10-17(20)21)6-4-5-7-16-15(11-19)18(22)23-16/h9-10,12,15-16,19H,4-8,11H2,1-3H3,(H,20,21)/b13-9+,14-10+/t12-,15-,16-/m1/s1
SMILES	C[C@H](CCCC[C@@H]1[C@H](C(=O)O1)CO)C/C(=C/C(=C/C(=O)O)/C)/C

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