Honokiol

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产品名称: Honokiol

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简单介绍

CAS:35354-74-6Formula:C18H18O2MW:266.33Appearance:WhiteSolidPurity:97%byHPLC

Honokiol 的详细介绍

Present as an active principle in the plant Magnolia grandiflora. Displays anxiolytic, antithrombotic, anti-tumor properties, etc. modulates the NF-B activation pathway, an upstream effector VEGF, COX-2, and MCL1, all significant pro-angiogenic and survival factors. Honokiol induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of doxorubicin and other etoposides.

Additional Information

Synonyms	2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol; HNK; Houpa
Product #	H-2355
CAS #	35354-74-6
Chemical Name	2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol; HNK; Houpa
Formula	C₁₈H₁₈O₂
MW	266.33
Appearance	White Solid
Purity	97% by HPLC
Solubility	DMSO (10 mg/ml) or EtOH
Melting Point	86-86.5 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent

Additional Information

MDL Number	MFCD00016674
ChemACX	X1277270-6
InChI	InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
SMILES	C=CCc1ccc(c(c1)c2ccc(c(c2)CC=C)O)O

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