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Hh Signaling Pathway Antagonist

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产品名称: Hh Signaling Pathway Antagonist
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简单介绍

CAS:330796-24-2Formula:C23H15ClF4N4O2MW:490.84Appearance:Whitetooff-whiteSolidPurity:97%byHPLC


Hh Signaling Pathway Antagonist  的详细介绍
Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC= 70 nM).

Additional Information

SynonymsN-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea
Product #H-2354
CAS #330796-24-2
Chemical NameN-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea
FormulaC23H15ClF4N4O2
MW490.84
AppearanceWhite to off-white Solid
Purity97% by HPLC
SolubilitySoluble in DMSO
Storage Temp+4°C
UseIt is a potent modulator of Hedgehog (Hh) protein function and a nanomolar hedgehog antagonist

Additional Information

MDL NumberMFCD10567691
ChemACXX1823651-2
InChIInChI=1S/C23H15ClF4N4O2/c24-18-10-7-14(11-17(18)23(26,27)28)30-22(34)29-12-20-31-19-4-2-1-3-16(19)21(33)32(20)15-8-5-13(25)6-9-15/h1-11H,12H2,(H2,29,30,34)
SMILESC1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F
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