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Herbimycin C

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产品名称: Herbimycin C
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简单介绍

CAS:91700-92-4Formula:C29H40N2O9MW:560.6Appearance:YellowsolidPurity:>98%byHPLC


Herbimycin C  的详细介绍
*Please inquire the availability for this product. Herbimycin C is a minor analogue of the herbimycin complex isolated from Streptomyces hygroscopicus. Herbimycin C possesses potent antitumor activity and converts Rous sarcoma virus-infected rat kidney cells into normal cells. Until now limited access has restricted a full investigation of the properties of herbimycin C. Research on related metabolites, herbimycin A and geldanamycin, has stimulated intensive interest in this class as selective antitumor agents and for prolonging the viability of tissue-cultured cells and organs.

Additional Information

SynonymsTAN 420D
Product #H-2471
CAS #91700-92-4
FormulaC29H40N2O9
MW560.6
AppearanceYellow solid
Purity>98% by HPLC
SolubilitySoluble in ethanol, methanol, DMF or DMSO Limited water solubility
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseMinor analog of the herbimycin complex with potent antitumor activity

Additional Information

MDL NumberMFCD14635436
InChIInChI=1S/C29H40N2O9/c1-15-9-8-10-22(37-5)27(40-29(30)36)17(3)11-16(2)24(33)23(38-6)12-18(4)26(39-7)20-13-19(32)14-21(25(20)34)31-28(15)35/h8-11,13-14,16,18,22-24,26-27,33H,12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8-,15-9+,17-11+/t16-,18-,22-,23-,24+,26+,27-/m0/s1
SMILESC[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\C=C(\C(=O)NC2=CC(=O)C=C([C@@H]1OC)C2=O)/C)OC)OC(=O)N)\C)C)O)OC
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