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Helenalin | CAS[6754-13-8] | Anti-inflammatory & Anti-Neoplastic Agent

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产品名称: Helenalin | CAS[6754-13-8] | Anti-inflammatory & Anti-Neoplastic Agent
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简单介绍

CAS:6754-13-8Formula:C15H18O4MW:262.3Appearance:Whitetooff-whiteSolidPurity:97%


Helenalin | CAS[6754-13-8] | Anti-inflammatory & Anti-Neoplastic Agent  的详细介绍

Potent anti-inflammatory and anti-neoplastic agent. Induces a CD95 death receptor-independent apoptosis even when the mitochondria protecting proteins Bcl-xL or Bcl-2 are overexpressed. Also an inhibitor of NF-B.

Additional Information

Product #H-1300
CAS #6754-13-8
Chemical Name(3AR,5R,5AR,8AR,9S,9AS)-9-HYDROXY-5,8A-DIMETHYL-1-METHYLIDENE-3A,4,5,5A,9,9A-HEXAHYDROAZULENO[6,7-B]FURAN-2,8-DIONE
FormulaC15H18O4
MW262.3
AppearanceWhite to off-white Solid
Purity97%
SolubilitySoluble in DMSO (10 mg/ml) or 100% ethanol.
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseAn inhibitor of the transcription factor NFκB is a potent antiinflammatory and antineoplastic agent

Additional Information

MDL NumberMFCD01674580
ChemACXX1021671-0
InChIInChI=1S/C15H18O4/c1-7-6-10-12(8(2)14(18)19-10)13(17)15(3)9(7)4-5-11(15)16/h4-5,7,9-10,12-13,17H,2,6H2,1,3H3/t7-,9+,10-,12-,13+,15+/m1/s1
SMILESC[C@@H]1C[C@@H]2[C@H]([C@@H]([C@]3([C@H]1C=CC3=O)C)O)C(=C)C(=O)O2
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