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Gossypol
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产品名称:
Gossypol
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简单介绍
CAS:303-45-7Formula:C30H30O8MW:518.6Appearance:Off-whitetoyellowSolidPurity:90%
Gossypol
的详细介绍
Shows anti-tumor, anti-viral and anti-oxidant actions. Small molecule inhibitor of Bcl-2/Bcl-XL. Induces apoptosis. Synergizes with radiation and chemotherapyin vitro. Also male antifertility agent.
Additional Information
Synonyms
2,2-bis[8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene]
Product #
G-1221
CAS #
303-45-7
Chemical Name
2,2’-
bis
[8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene]
Formula
C
30
H
30
O
8
MW
518.6
Appearance
Off-white to yellow Solid
Purity
90%
Solubility
Soluble in 100% Ethanol (25mg/ml); DMF, Acetone, or DMSO. Insoluble in Water.
Storage Temp
-20°C
Therapeutic Area
Oncological Disorders
Use
Gossypol Induces Apoptosis by Activating p53 in Prostate Cancer Cells
Additional Information
Merck Index
Merck Index: 14: 4528
MDL Number
MFCD00017352
ChemACX
X1009723-5
InChI
InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,33-38H,1-6H3
SMILES
Cc1cc2c(c(c(c(c2C(C)C)O)O)C=O)c(c1c3c(cc4c(c3O)c(c(c(c4C(C)C)O)O)C=O)C)O
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