Gilvocarcin V

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产品名称: Gilvocarcin V

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简单介绍

CAS:77879-90-4Formula:C27H26O9MW:494.5Appearance:YellowcrystalsPurity:>95%byHPLC

Gilvocarcin V 的详细介绍

*Please inquire the availability for this product. Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research suggests that the gilvocarcins act as photoactivated cross-linkers of DNA to histones.

Additional Information

Synonyms	Anandimycin A, Toromycin, 1072B
Product #	G-2519
CAS #	77879-90-4
Formula	C27H26O9
MW	494.5
Appearance	Yellow crystals
Purity	>95% by HPLC
Solubility	Soluble in DMSO, DMF (moderately), methanol (moderately), ethanol (moderately), and water (poor)
Melting Point	322.54 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A metabolite that displays potent antibacterial, antifungal and antiviral activity

Additional Information

MDL Number	MFCD01939442
InChI	InChI=1S/C27H26O9/c1-5-12-8-15-19(17(9-12)33-3)14-10-18(34-4)21-16(29)7-6-13(20(21)25(14)36-27(15)32)26-23(31)22(30)24(35-26)11(2)28/h5-11,22-24,26,28-31H,1H2,2-4H3/t11?,22?,23?,24?,26-/m1/s1
SMILES	CC(C1C(C([C@H](O1)c2ccc(c3c2c4c(cc3OC)c5c(cc(cc5OC)C=C)c(=O)o4)O)O)O)O

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