Gilvocarcin M

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产品名称: Gilvocarcin M

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简单介绍

CAS:77879-89-1Formula:C26H26O9MW:482.5Appearance:YellowLyophilisatePurity:>95%byHPLC

Gilvocarcin M 的详细介绍

*Please inquire the availability for this product. Gilvocarcin M is the minor analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin M contains a methyl group in the 8-position, and is less active than the vinyl analogue (gilvocarcin V), which is thought to act as an inhibitor of human topoisomerase II. Gilvocarcin M displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research suggests that the gilvocarcins act as photoactivated cross-linkers of DNA to histones.

Additional Information

Synonyms	Anandimycin B, Toromycin B, 1072A
Product #	G-2517
CAS #	77879-89-1
Formula	C26H26O9
MW	482.5
Appearance	Yellow Lyophilisate
Purity	>95% by HPLC
Solubility	Soluble in DMF, DMSO, methanol (slightly), and 100% ethanol (slightly)
Melting Point	319.72 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	Gilvocarcin M displays potent antibacterial, antifungal, antiviral and antitumor activity

Additional Information

MDL Number	MFCD01662195
InChI	InChI=1S/C26H26O9/c1-10-7-14-18(16(8-10)32-3)13-9-17(33-4)20-15(28)6-5-12(19(20)24(13)35-26(14)31)25-22(30)21(29)23(34-25)11(2)27/h5-9,11,21-23,25,27-30H,1-4H3/t11-,21+,22-,23+,25-/m1/s1
SMILES	Cc1cc2c(c3cc(c4c(ccc(c4c3oc2=O)[C@@H]5[C@@H]([C@@H]([C@@H](O5)[C@@H](C)O)O)O)O)OC)c(c1)OC

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