Ganciclovir

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产品名称: Ganciclovir

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简单介绍

CAS:82410-32-0Formula:C9H13N5O4MW:255.23Appearance:AcrystallinewhitesolidPurity:≥95%

Ganciclovir 的详细介绍

An acyclic analog of the nucleoside guanosine, chemically related to acyclovir. It inhibits the replication of viruses including CMV, Herpes Simplex, Varicella Zoster and Epstein-Barr. It inhibits virus replication by its incorporation into viral DNA. This incorporation inhibits dATP and leads to defective DNA, ceasing or retarding the viral machinery required to spread the virus to other cells.

Additional Information

Product #	G-2431
CAS #	82410-32-0
Chemical Name	2-Amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-3H-purin-6-one
Formula	C₉H₁₃N₅O₄
MW	255.23
Appearance	A crystalline white solid
Purity	≥ 95%
Solubility	Soluble in DMSO (~5 mg/ml) or H₂O (~ 5 mg/ml)
Storage Temp	+4°C
Therapeutic Area	Infectious Diseases
Use	Ganciclovir used to study the loss of telomeres and to evaluate sensitivity of viruses to antiviral agents.

Additional Information

MDL Number	MFCD00870588
ChemACX	X1004235-0
InChI	InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
SMILES	c1nc2c(=O)[nH]c(nc2n1COC(CO)CO)N

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