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Fostriecin
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产品名称:
Fostriecin
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简单介绍
CAS:87810-56-8Formula:C19H26NaO9PMW:452.4Appearance:WhitepowderPurity:>95%byHPLC
Fostriecin
的详细介绍
Fostriecin is the most fully characterised member of a family of phosphate esters of a triene antibiotic. The antitumor potential of fostriecin has attracted considerable interest, focused on its mode of action as a topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein phosphatase PP2A.
Additional Information
Synonyms
Phosphotrienin, CI 920, CL 1565A, PD 110161, NSC 339638
Product #
F-2437
CAS #
87810-56-8
Formula
C19H26NaO9P
MW
452.4
Appearance
White powder
Purity
>95% by HPLC
Solubility
Soluble in water (100 mM), and methanol
Storage Temp
-20°C
Therapeutic Area
Infectious Diseases
Use
Fostriecin is an antibiotic
Additional Information
MDL Number
MFCD01939908
InChI
InChI=1S/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2-,6-4+,8-5-,12-11+;/t15-,16+,17+,19+;/m0./s1
SMILES
C[C@](C=C[C@H]1CC=CC(=O)O1)([C@@H](C[C@H](C=CC=CC=CCO)O)O[P](=O)(O)[O-])O.[N a+]
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