Fostamatinib Disodium

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产品名称: Fostamatinib Disodium

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简单介绍

CAS:1025687-58-4Formula:C23H24FN6O9PNa2MW:624.42Appearance:Off-whitesolidPurity:≥98%byHPLC

Fostamatinib Disodium 的详细介绍

A potent, ATP-competitive and selective Syk (Spleen tyrosine kinase) inhibitor (IC₅₀ = 41 nM). Inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling.

Additional Information

Product #	F-2331
CAS #	1025687-58-4
Chemical Name	(6-((5-Fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl dihydrogen phosphate, disodium
Formula	C₂₃H₂₄FN₆O₉PNa₂
MW	624.42
Appearance	Off-white solid
Purity	≥98% by HPLC
Solubility	DMSO
Storage Temp	-20°C

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