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Filipin II
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Filipin II
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简单介绍
CAS:38620-77-8Formula:C35H58O10MW:638.8Appearance:YellowsolidPurity:>95%byHPLC
Filipin II
的详细介绍
*Please inquire the availability for this product. Filipin II is a minor component of the filipin complex, a family of pentaene antifungal metabolites first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Structurally, filipin II lacks the hydroxy moiety on the pentyl side chain and is more hydrophobic, eluting later than filipin III on reverse phase HPLC. Filipin II is a potent broad spectrum antifungal agent that also exhibits antitumor and antiviral activities and acts by binding cell membrane sterols, disrupting membrane integrity.
Additional Information
Product #
F-2429
CAS #
38620-77-8
Formula
C35H58O10
MW
638.8
Appearance
Yellow solid
Purity
>95% by HPLC
Storage Temp
-20°C
Therapeutic Area
Infectious Diseases
Use
Filipin II is a potent broad spectrum antifungal agent
Additional Information
InChI
InChI=1S/C35H58O10/c1-4-5-6-13-16-31-34(43)23-30(40)21-28(38)19-26(36)18-27(37)20-29(39)22-33(42)24(2)15-12-10-8-7-9-11-14-17-32(41)25(3)45-35(31)44/h7-12,14-15,17,25-34,36-43H,4-6,13,16,18-23H2,1-3H3/b8-7+,11-9+,12-10+,17-14+,24-15+/t25-,26+,27-,28+,29?,30+,31-,32+,33+,34+/m1/s1
SMILES
CCCCCC[C@@H]1[C@H](C[C@H](C[C@H](C[C@H](C[C@H](CC(C[C@@H](/C(=C/C=C/C=C/C=C/C=C/[C@@H]([C@H](OC1=O)C)O)/C)O)O)O)O)O)O)O
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