Etoposide

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产品名称: Etoposide

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简单介绍

CAS:33419-42-0Formula:C29H32O13MW:588.6Appearance:WhitesolidPurity:>98%

Etoposide 的详细介绍

Topoisomerase II inhibitor. Anti-tumor reagent. Widely used apoptosis inducer by FasL. Semisynthetically derived frompodophyllotoxin.

Synonyms	VP-16-213
Product #	E-2004
CAS #	33419-42-0
Chemical Name	4-Desmethylepipodophyllotoxin 9-(4,6-0-ethylidene)-½‚²- D-glucopyranoside
Formula	C₂₉H₃₂O₁₃
MW	588.6
Appearance	White solid
Purity	>98%
Solubility	Soluble in DMSO (25mg/ml)
Melting Point	236-251 °C
Storage Temp	Store desiccated as supplied at -20°C for up to 2 years
Therapeutic Area	Oncological Disorders
Use	Inhibits DNA synthesis via topoisomerase II inhibition used as a form of chemotherapy for cancers

MDL Number	MFCD00869325
ChemACX	X1004425-4
InChI	InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
SMILES	C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@@H]3c4cc5c(cc4[C@H]([C@@H]6[C@@H]3COC6=O)c7cc(c(c(c7)OC)O)OC)OCO5)O)O

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