Equisetin, Fusarium equiseti

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产品名称: Equisetin, Fusarium equiseti

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简单介绍

CAS:57749-43-6Formula:C22H31NO4MW:373.5Appearance:TanLyophilisatePurity:99%byHPLC

Equisetin, Fusarium equiseti 的详细介绍

The tetramic acid, Equisetin, is produced by a number of species of Fusarium. Interest in equisetin emerged with reports of its inhibitory activity against human immunodeficiency virus type 1 (HIV-1) integrasein vitro that was mechanistically distinct from previously described inhibitors. Equisetin inhibits 3' end-processing and strand transfer as well as disintegration catalysed by either the full-length enzyme or the truncated integrase core. Newly isolated microbial agent.

Additional Information

Product #	E-2028
CAS #	57749-43-6
Chemical Name	(2S)-4-(((1S,2R,4AS,6R,8AR)-1,6-DIMETHYL-2-[(1E)-1-PROPEN-1-YL]-1,2,4A,5,6,7,8,8A-OCTAHYDRO-1-NAPHTHALENYL)CARBONYL)-5-HYDROXY-2-(HYDROXYMETHYL)-1-METHYL-1,2-DIHYDRO-3H-PYRROL-3-ONE
Formula	C₂₂H₃₁NO₄
MW	373.5
Appearance	Tan Lyophilisate
Purity	99% by HPLC
Solubility	Soluble in Water, Ethanol, Acetone, Ethyl Acetate
Melting Point	223.22 °C
Storage Temp	+4°C
Therapeutic Area	Infectious Diseases
Use	A tetramic acid with antibiotic and cytotoxic activity, and a potent inhibitor of HIV-1 integrase

Additional Information

MDL Number	MFCD01729357
ChemACX	X1751797-2
InChI	InChI=1S/C22H31NO4/c1-5-6-15-9-8-14-11-13(2)7-10-16(14)22(15,3)20(26)18-19(25)17(12-24)23(4)21(18)27/h5-6,8-9,13-17,24,27H,7,10-12H2,1-4H3/b6-5+/t13-,14-,15-,16-,17+,22-/m1/s1
SMILES	C/C=C/[C@@H]1C=C[C@@H]2C[C@@H](CC[C@H]2[C@]1(C)C(=O)C3=C(N([C@H](C3=O)CO)C)O)C

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