Epothilone A

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产品名称: Epothilone A

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简单介绍

CAS:152044-53-6Formula:C26H39NO6SMW:493.7Appearance:WhitetooffwhitepowderPurity:>98%byHPLC

Epothilone A 的详细介绍

*Please inquire the availability for this product. Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A acts by stabilising microtubule formation at the taxol , and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Epothilone A has been investigated in clinical trials as an antitumor agent.

Additional Information

Synonyms	EpoA
Product #	E-2447
CAS #	152044-53-6
Formula	C₂₆H₃₉NO₆S
MW	493.7
Appearance	White to off white powder
Purity	>98% by HPLC
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	The epothilones are a novel class of antineoplastic agents

Additional Information

MDL Number	MFCD09970958
InChI	InChI=1S/C26H39NO6S/c1-14-8-7-9-19-21(32-19)11-20(15(2)10-18-13-34-17(4)27-18)33-23(29)12-22(28)26(5,6)25(31)16(3)24(14)30/h10,13-14,16,19-22,24,28,30H,7-9,11-12H2,1-6H3/b15-10+/t14-,16+,19+,20-,21-,22-,24-/m1/s1
SMILES	Cc1nc(cs1)/C=C(\C)/[C@H]2C[C@@H]3[C@@H](O3)CCC[C@H]([C@H]([C@@H](C(=O)C([C@@H](CC(=O)O2)O)(C)C)C)O)C

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